Deadly Pills: A National Epidemic















01/19/2013 at 04:00 PM EST







Jace Uher-Flom's mom dies two weeks after her birth of an overdose of prescription drugs


Grant Delin


Drugs are now the No. 1 accidental killer in the U.S., with the vast majority of deaths caused by prescription meds. A look at how medicines that are now a part of everyday life can also turn families upside down forever.

The statistics are staggering, the medicines powerful and highly addictive: This year more Americans will die of drug over-doses than in any other type of accident – including car crashes. In most cases, those deaths are caused by pills in many people's medicine cabinets given to them by trusted doctors, left over from routine surgeries or prescribed to manage chronic conditions.

"Prescription drug overdoses are a serious nationwide problem," says Dr. Leonard Paulozzi of the C.D.C.'s National Center for Injury Prevention and Control, "for which we haven't yet found a solution."

How did we get here? For the millions of Americans who suffer from chronic pain, heavy-duty painkillers are the wonder drugs that help them lead more comfortable lives. But in the past 20 years, as opiate painkillers have become more routinely prescribed, the number of people dying from them – as a result of misuse or accidentally – has skyrocketed.

Often those deaths are due to bad interactions with other substances: Combined with alcohol some antidepressants can cause dangerous spikes in blood pressure, and mixing pain pills with a few drinks "can depress the brain," says Paulozzi, "and lead to death."

It's a problem even the drug industry acknowledges, says Sharon Brigner, of the Pharmaceutical Research and Manufacturers of America: "These medicines can be an important tool – we tell anyone we talk to that medicines save and improve lives every day. But if misused, they can kill."

Read More..

Lilly drug chosen for Alzheimer's prevention study


Researchers have chosen an experimental drug by Eli Lilly & Co. for a large federally funded study testing whether it's possible to prevent Alzheimer's disease in older people at high risk of developing it.


The drug, called solanezumab (sol-ah-NAYZ-uh-mab), is designed to bind to and help clear the sticky deposits that clog patients' brains.


Earlier studies found it did not help people with moderate to severe Alzheimer's but it showed some promise against milder disease. Researchers think it might work better if given before symptoms start.


"The hope is we can catch people before they decline," which can come 10 years or more after plaques first show up in the brain, said Dr. Reisa Sperling, director of the Alzheimer's center at Brigham and Women's Hospital in Boston.


She will help lead the new study, which will involve 1,000 people ages 70 to 85 whose brain scans show plaque buildup but who do not yet have any symptoms of dementia. They will get monthly infusions of solanezumab or a dummy drug for three years. The main goal will be slowing the rate of cognitive decline. The study will be done at 50 sites in the U.S. and possibly more in Canada, Australia and Europe, Sperling said.


In October, researchers said combined results from two studies of solanezumab suggested it might modestly slow mental decline, especially in patients with mild disease. Taken separately, the studies missed their main goals of significantly slowing the mind-robbing disease or improving activities of daily living.


Those results were not considered good enough to win the drug approval. So in December, Lilly said it would start another large study of it this year to try to confirm the hopeful results seen patients with mild disease. That is separate from the federal study Sperling will head.


About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.


___


Online:


Alzheimer's info: http://www.alzheimers.gov


Alzheimer's Association: http://www.alz.org


___


Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP


Read More..

Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.


The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.


Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.


Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.


"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.


Major technology companies also report next week, but the bar for the sector has been lowered even further.


Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.


Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.


Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.


CASH POURING IN, HOUSING DATA COULD HELP


Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.


The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.


"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.


"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."


Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.


Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.


The new home sales report on Friday is expected to show a 2.1 percent increase.


The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.


Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.


The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.


"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.


"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."


(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)



Read More..

In Which Actual Joe Biden and ‘Onion’ Joe Biden Pal Around on Reddit and Twitter






The Onion‘s brilliant creation, “Diamond” Joe Biden, stopped by Reddit, in character, for one of the site’s signature Ask Me Anything sessions on Friday afternoon. And, hey, look who asked something over Twitter just as the AMA began:



Q for @reddit AMA with my @theonion pal: A Trans-Am? Ever look under the hood of a Corvette? #imavetteguy –VP twitter.com/VP/status/2923…






— Office of VP Biden (@VP) January 18, 2013


So that happened, and it’s so beyond meta that our heads hurt. It confirms that the vice-president (or at least his office) is aware of his satirical alter-ego: the foul-mouthed, Trans-Am-driving, skirt-chaser known to hundreds of Onion articles. And, of course, “Diamond” Joe answered:


RELATED: The Real Joe Biden vs. The Onion’s Joe Biden: A Quiz


So why would Actual Joe Biden indulge the funniest incarnation of the Uncle Joe Biden whom the Internet loves so much? Maybe he thinks he’s funny! After all, Actual Joe Biden is pretty funny himself, and “Diamond” Joe’s answers on Reddit this afternoon didn’t disappoint. Some highlights:


RELATED: The Gingriches Endorse Meryl Streep; Alec Baldwin’s Mayoral Two-Step


And another:


RELATED: How Joe Biden Stages Those Average-Joe Pictures… in Pictures


8eade  4f2570aadcda87ffa174c9e396a9a743 640x138 In Which Actual Joe Biden and Onion Joe Biden Pal Around on Reddit and Twitter


One more:


8eade  d8f4bc9006a58d7fb7023f4b958f4ba5 640x137 In Which Actual Joe Biden and Onion Joe Biden Pal Around on Reddit and Twitter


And, yes, there’s a theme here:


8eade  95a4b46ca936267d4f43e3122923cd2d 640x188 In Which Actual Joe Biden and Onion Joe Biden Pal Around on Reddit and Twitter


Social Media News Headlines – Yahoo! News




Read More..

Nicholas Hoult: The Brains in My New Zombie Movie Were 'Pretty Tasty'




It's the age-old story: Boy meets girl. Boy falls in love with girl. Girl has trouble introducing the boy to her best friend, because the boy is a zombie and ate her last boyfriend.

Wait, what?

In the upcoming comedy Warm Bodies, Nicholas Hoult (A Single Man, X-Men First Class) plays R, a lonely zombie who is dissatisfied with his life of shuffling around an airport, eating brains and grunting out conversations with his best friend (Rob Corddry).

But R's still heart begins to beat when he lays eyes on Julie (Teresa Palmer), the daughter of a zombie-killing general and girlfriend of R's last meal. So he embarks on a mission to befriend Julie and, as he haltingly reminds her, "keep safe."

"I understood that feeling of wanting to connect and caring about someone a lot and wanting to look after them," Hoult tells PEOPLE about why he chose the role. "The great thing about [Julie] is she's bubbly and there's a spark about her. And she's obviously very open to the world around her, and I think that's a good thing. She's positive."

Julie and R form an unlikely bond, with Julie's best friend Nora (Crazy, Stupid, Live's Analeigh Tipton) giving him the requisite inquisition before accepting that R is, indeed, good.

"As much as [Julie is] saving my character and making him human again, she's just as trapped in the human world where the humans have gone down this road of closing themselves in and giving up on finding a cure," says Hoult. "She's the one person who steps out from the crowd and sees hope in my character."

But it's not all romantic glances and swoony zombie love – since R meets Julie after dining on her boyfriend Perry (Dave Franco). And yes, there is the requisite brain-eating (but Warm Bodies delivers a good reason for why the undead prefer the gray matter).

"It was kind of a wet, soft, cold cake mixed with grapefruit and peachy stuff," Hoult says of filming those scenes. "It was quite sweet. Pretty tasty. It's going to be one of my odd requests wherever I go. 'Delicious brains,' please!"

Warm Bodies opens Feb 1.

Read More..

Flu season 'bad one for the elderly,' CDC says


The number of older people hospitalized with the flu has risen sharply, prompting federal officials to take unusual steps to make more flu medicines available and to urge wider use of them as soon as symptoms appear.


The U.S. is about halfway through this flu season, and "it's shaping up to be a worse-than-average season" and a bad one for the elderly, said Dr. Thomas Frieden, director of the Centers for Disease Control and Prevention.


It's not too late to get a flu shot, and "if you have symptoms, please stay home from work, keep your children home from school" and don't spread the virus, he said.


New figures from the CDC show widespread flu activity in all states but Tennessee and Hawaii. Some parts of the country are seeing an increase in flu activity "while overall activity is beginning to go down," Frieden said. Flu activity is high in 30 states and New York City, up from 24 the previous week.


Nine more children or teens have died of the flu, bringing the nation's total this flu season to 29. That's close to the 34 pediatric deaths reported during all of the last flu season, although that one was unusually light. In a typical season, about 100 children die of the flu and officials said there is no way to know whether deaths this season will be higher or lower than usual.


The government doesn't keep a running tally of adult deaths from the flu, but estimates that it kills about 24,000 people most years.


So far, half of confirmed flu cases are in people 65 and older. Lab-confirmed flu hospitalizations totaled 19 for every 100,000 in the population, but 82 per 100,000 among those 65 and older, "which is really quite a high rate," Frieden said.


"We expect to see both the number and the rates of both hospitalizations and deaths rise further in the next week or so as the flu epidemic progresses,'" so prompt treatment is key to preventing deaths, he said.


About 90 percent of flu deaths are in the elderly; the very young and people with other health problems such as diabetes are also at higher risk.


If you're worried about how sick you are and are in one of these risk groups, see a doctor, Frieden urged. One third to one half of people are not getting prompt treatment with antiviral medicines, he said.


Two drugs — Tamiflu and Relenza — can cut the severity and risk of death from the flu but must be started within 48 hours of first symptoms to do much good. Tamiflu is available in a liquid form for use in children under 1, and pharmacists can reformulate capsules into a liquid if supplies are short in an area, said Dr. Margaret Hamburg, head of the Food and Drug Administration.


To help avoid a shortage, the FDA is letting Tamiflu's maker, Genentech, distribute 2 million additional doses of capsules that have an older version of package insert.


"It is fully approved, it is not outdated," just lacks information for pharmacists on how to mix it into a liquid if needed for young children, she said.


This year's flu season started about a month earlier than normal and the dominant flu strain is one that tends to make people sicker. Vaccinations are recommended for anyone 6 months or older. There's still plenty of vaccine — an update shows that 145 million doses have been produced, "twice the supply that was available only several years ago," Hamburg said.


About 129 million doses have been distributed already, and a million doses are given each day, Frieden said. The vaccine is not perfect but "it's by far the best tool we have to prevent influenza," he said.


Carlos Maisonet, 73, got a flu shot this week at New York's Brooklyn Hospital Center at the urging of his wife, who was vaccinated in August.


"This is his first time getting the flu shot," said his wife, Zulma Ramos.


Last week, the CDC said the flu again surpassed an "epidemic" threshold, based on monitoring of deaths from flu and a frequent complication, pneumonia. The flu epidemic happens every year and officials say this year's vaccine is a good match for strains that are going around.


___


Online:


Flu vaccine finder: http://www.flu.gov


CDC flu info: http://www.cdc.gov/flu/index.htm


___


AP Photographer Bebeto Matthews in New York contributed to this report.


___


Follow Marilynn Marchione's coverage at —http://twitter.com/MMarchioneAP


Read More..

Dow, S&P 500 end at five-year highs on early earnings beats

NEW YORK (Reuters) - The Dow and S&P 500 closed at five-year highs on Friday as the market registered a third straight week of gains on a solid start to the quarterly earnings season.


Morgan Stanley was the latest Wall Street bank to report strong results. Its better-than-expected earnings followed similar report cards from Goldman Sachs and JP Morgan Chase earlier in the week.


Shares of Morgan Stanley shot up 7.9 percent to $22.38. It reported a fourth-quarter profit after a year-earlier loss, helped by higher revenue at the bank's institutional securities business.


But Friday's rise was held back by shares of Intel Corp , which slumped 6.3 percent to $21.25 a day after it forecast quarterly revenue below analysts' estimates and announced plans for increased capital spending amid slow demand for personal computers.


Another factor that has been weighing on the market before a three-day weekend is uncertainty about the federal debt limit and spending cuts that could hamper U.S. growth. U.S. markets will be closed on Monday for the Martin Luther King Jr. holiday.


There were signs on Friday that the question of raising the U.S. debt limit would be put off for a while. House Republican leaders said they would seek to pass a three-month extension of federal borrowing authority next week to buy time for the Democratic-controlled Senate to pass a budget that shrinks deficits.


"It could be a big positive for the markets if we come up wih a plan of spending cuts that isn't too awfully hard on the economy," said Bryant Evans, investment adviser and portfolio manager at Cozad Asset Management, in Champaign, Illinois.


The Dow Jones industrial average <.dji> was up 53.68 points, or 0.39 percent, at 13,649.70. The Standard & Poor's 500 Index <.spx> was up 5.04 points, or 0.34 percent, at 1,485.98. The Nasdaq Composite Index <.ixic> was down 1.30 points, or 0.04 percent, at 3,134.71.


The Dow and S&P 500 ended at their highest levels since December 2007. For the week, the Dow ended up 1.2 percent, the S&P 500 ended up 0.9 percent and the Nasdaq ended up 0.3 percent.


The CBOE Volatility index <.vix>, Wall Street's so-called fear gauge, fell 8.2 percent. The VIX usually moves inversely to the S&P 500 as it is used as a hedge against further market decline.


Also reporting stronger-than-expected earnings on Friday was General Electric , whose shares rose 3.5 percent to $22.04.


Overall, S&P 500 fourth-quarter earnings are forecast to have risen 2.5 percent, according to Thomson Reuters data. [ID:nL1E9CI581] That estimate is above the 1.9 percent forecast from a week ago but well below the 9.9 percent fourth-quarter earnings forecast from October 1, the data showed.


Economic data from China also provided some support to the market, though the focus remained on U.S. corporate earnings. China's economy grew at a modestly faster-than-expected 7.9 percent in the fourth quarter, the latest sign the world's second-biggest economy was pulling out of a post-global financial crisis slowdown which saw it grow in 2012 at its weakest pace since 1999.


Despite the gains by Morgan Stanley, financial stocks sagged as Capital One Financial reported disappointing profit. Capital One slumped 7.5 percent to $56.99, while the KBW bank index <.bkx> slipped 0.3 percent.


Volume was roughly 6.6 billion shares traded on the New York Stock Exchange, the Nasdaq and the NYSE MKT, compared with the 2012 average daily closing volume of about 6.45 billion.


Advancers outpaced decliners on the NYSE by nearly 2 to 1 and on the Nasdaq by about 13 to 11.


(Additional reporting by Angela Moon; Editing by Bernadette Baum, Kenneth Barry and Nick Zieminski)



Read More..

Some foreign hostages said killed in Algeria assault


ALGIERS (Reuters) - Algeria said several hostages were killed on Thursday when its forces stormed a remote desert gas plant occupied by Islamist militants in retaliation for French intervention in Mali, and local sources said six foreigners were among the dead.


Amid reports of many more casualties in one of the biggest international hostage crises in decades, Western leaders expressed anger they had not been consulted before the operation and scrambled for word of their citizens. Some eight hours after the army assault began, Algerian state media said it was over.


Americans, Britons, Norwegians, French, Romanians and an Austrian, were among those taken, their countries said.


Algeria said its troops had been forced to act to free them due to the "diehard" attitude of their captors.


"When the terrorist group insisted on leaving the facility, taking the foreign hostages with them to neighboring states, the order was issued to special units to attack the position where the terrorists were entrenched," the government spokesman, Communication Minister, Mohamed Said told the state news agency.


The standoff began when gunmen calling themselves the Battalion of Blood stormed the natural gas facility early on Wednesday morning. They said they were holding 41 foreigners and demanded a halt to a French military operation against fellow al Qaeda-linked Islamist militants in neighboring Mali.


Said said the military operation, which Western officials were told had begun around noon (6:00 a.m. EST) on Thursday, resulted in "the liberation of a large number of hostages and the destruction of a large number of terrorists".


The raid increased fears jihadist militants could launch further attacks in Algeria, a vast desert country with large oil and gas reserves that is only just recovering from a protracted conflict with Islamist rebels during the 1990s which cost an estimated 200,000 lives.


A local source told Reuters six foreign hostages were killed along with eight captors when the Algerian military fired on a vehicle being used by the gunmen.


He said 40 Algerians and three foreigners were freed by the army as it continued its operation into Thursday evening. An Algerian security source said earlier that 25 foreign hostages had escaped.


Algeria's official APS news agency said about half the foreign hostages had been freed and about 600 Algerian workers at the site, under less tight guard, had managed to escape.




MILITANTS KNEW THEIR WAY AROUND


In a rare eyewitness account of Wednesday's raid, a local man who had escaped from the facility told Reuters the militants appeared to have good inside knowledge of the layout of the complex and used the language of radical Islam.


"The terrorists told us at the very start that they would not hurt Muslims but were only interested in the Christians and infidels," Abdelkader, 53, said by telephone from his home in the nearby town of In Amenas. "We will kill them, they said."


Mauritanian agency ANI and Qatar-based Al Jazeera said that 34 of the captives and 15 of their captors had been killed when government forces fired from helicopters at a vehicle.


Those death tolls, far higher than confirmed by the local source, would contradict the reports that large numbers of foreigners escaped alive. On Thursday evening, ANI said it had lost its previously regular contact with the kidnappers.


Britain and Norway, whose oil firms BP and Statoil run the plant jointly with the Algerian state oil company, said they had been informed by the Algerian authorities that a military operation was under way.


British Prime Minister David Cameron said people should prepare for bad news about the hostages. He earlier called his Algerian counterpart to express his concern at what he called a "very grave and serious" situation, Cameron's spokesman said.


"The Algerians are aware that we would have preferred to have been consulted in advance," the spokesman added.


Norwegian Prime Minister Jens Stoltenberg said he had been told by his Algerian counterpart the action had started at around noon. He said they had tried to find a solution through the night, but that it had not worked.


"The Algerian prime minister said they felt they had no choice but to go in now," he said.


RAISING THE STAKES


The incident dramatically raises the stakes in the French military campaign in neighboring Mali, where hundreds of French paratroopers and marines are launching a ground offensive against Islamist rebels after air strikes began last week.


"What is happening in Algeria justifies all the more the decision I made in the name of France to intervene in Mali in line with the U.N. charter," French President Francois Hollande said, adding that things seemed to have taken a "dramatic" turn and he was still seeking details.


He said earlier that an unspecified number of French nationals were among the hostages. A French national was also among the hostage takers, a local source told Reuters. A large number of people from the former French colony live in France.


Algerian Interior Minister Daho Ould Kablia said the kidnappers were led by Mokhtar Belmokhtar, a veteran Islamist guerrilla who fought in Afghanistan and set up his own group in the Sahara after falling out with other local al Qaeda leaders.


A holy warrior-cum-smuggler dubbed "The Uncatchable" by French intelligence and "Mister Marlboro" by some locals for his illicit cigarette-running business, Belmokhtar's links to those who seized towns across northern Mali last year are unclear.


A local source told Reuters the hostage takers had blown up a petrol filling station at the plant.


NUMBERS UNCONFIRMED


The precise number and nationalities of foreign hostages could not be confirmed, with some countries reluctant to release information that could be useful to the captors.


Britain said one of its citizens was killed in the initial storming on Wednesday and "a number" of others were held.


The militants had said seven Americans were among their hostages. The White House said it believed Americans were among those held but U.S. officials could not confirm the number. "This is an ongoing situation and we are seeking clarity," White House spokesman Jay Carney told reporters, expressing concern about the reported loss of lives.


Statoil said it had no word on nine of its Norwegian staff who had been held but that three Algerian employees were now free. BP said some of its staff were held but would not say how many or their nationalities.


Japanese media said five workers from Japanese engineering firm JGC Corp. were held, a number the company did not confirm. Vienna said one hostage was Austrian, Dublin said one Irish hostage had been freed and Bucharest said an unspecified number of those held were Romanian.


BP, Statoil and Spanish oil company Cepsa all said they had begun to evacuate personnel from elsewhere in Algeria, an OPEC member.


Hollande has received public backing from Western and African allies who fear that al Qaeda, flush with men and arms from the defeated forces of Libya's Muammar Gaddafi, is building a desert haven in Mali, a poor country helpless to combat fighters who seized its northern oasis towns last year.


However, there is also some concern in Washington and other capitals that the French action in Mali could provoke a backlash worse than the initial threat by militants in the remote Sahara.


The militants, communicating through established contacts with media in neighboring Mauritania, said on Wednesday they had dozens of men armed with mortars and anti-aircraft missiles in the compound and had rigged it with explosives.


They condemned Algeria's secularist government for letting French warplanes fly over its territory to Mali and shutting its border to Malian refugees.


The attack in Algeria did not stop France from pressing on with its campaign in Mali. It said on Thursday it now had 1,400 troops on the ground in Mali, and combat was under way against the rebels that it first began targeting from the air last week.


The French action last week came as a surprise but received widespread international support in public. Neighboring African countries planning to provide ground troops for a U.N. force by September have said they will move faster to deploy them.


Nigeria, the strongest regional power, sent 162 soldiers on Thursday, the first of an anticipated 906.


A day after launching the campaign in Mali, Hollande also ordered a failed rescue in Somalia on Saturday to free a French hostage held by al Qaeda-linked al Shabaab militants since 2009. Al Shabaab said on Thursday it had executed hostage Denis Allex. France said it believed he died in the rescue.


(Additional reporting by Ali Abdelatti in Cairo, Gwladys Fouche in Oslo, Mohammed Abbas in London and Padraic Halpin in Writing by Peter Graff, Giles Elgood and Philippa Fletcher; Editing by Alastair Macdonald)



Read More..

Britney Spears & Jason Trawick Split: Will She Be Okay?















01/17/2013 at 04:45 PM EST







Britney Spears and Jason Trawick


Michael Kovac/Getty


The new year has already been full of change for Britney Spears.

"She's left her gig as judge on The X Factor, her new puppy Hannah is gravely ill, and on Jan. 11 she announced she and fiancé Jason Trawick, 41, have called it quits after more than three years together.

While Spears, 31, told PEOPLE in an exclusive statement, "I'll always adore him, and we will remain great friends," a family source says the signer is "definitely upset about the split."

What tore the couple apart? Spears, who has two sons with ex-husband Kevin Federline, had hoped to start a family soon with Trawick, but he wasn't ready. Says the close source: "There were so many issues he wanted worked out before that" – including her neediness. "It was difficult for Jason to have his own life."

Adds an insider: "Britney is very insecure and has had a lot of trouble with jealousy." These insecurities may be heightened now. "[She] is very worried about being alone," says the family source. "She is upset, but for a long time she has treated him like a friend, not a romantic partner." The family source adds that some close to the singer, who had a breakdown in 2008, "are concerned about her future."

Read More..

Will Obama's order lead to surge in gun research?


MILWAUKEE (AP) — Nearly as many Americans die from guns as from car crashes each year. We know plenty about the second problem and far less about the first. A scarcity of research on how to prevent gun violence has left policymakers shooting in the dark as they craft gun control measures without much evidence of what works.


That could change with President Barack Obama's order Wednesday to ease research restrictions pushed through long ago by the gun lobby. The White House declared that a 1996 law banning use of money to "advocate or promote gun control" should not keep the Centers for Disease Control and Prevention and other federal agencies from doing any work on the topic.


Obama can only do so much, though. Several experts say Congress will have to be on board before anything much changes, especially when it comes to spending money.


How severely have the restrictions affected the CDC?


Its website's A-to-Z list of health topics, which includes such obscure ones as Rift Valley fever, does not include guns or firearms. Searching the site for "guns" brings up dozens of reports on nail gun and BB gun injuries.


The restrictions have done damage "without a doubt" and the CDC has been "overly cautious" about interpreting them, said Daniel Webster, director of the Center for Gun Policy and Research at the Johns Hopkins Bloomberg School of Public Health.


"The law is so vague it puts a virtual freeze on gun violence research," said a statement from Michael Halpern of the Union of Concerned Scientists. "It's like censorship: When people don't know what's prohibited, they assume everything is prohibited."


Many have called for a public health approach to gun violence like the highway safety measures, product changes and driving laws that slashed deaths from car crashes decades ago even as the number of vehicles on the road rose.


"The answer wasn't taking away cars," said Dr. Georges Benjamin, executive director of the American Public Health Association.


However, while much is known about vehicles and victims in crashes, similar details are lacking about gun violence.


Some unknowns:


—How many people own firearms in various cities and what types.


—What states have the highest proportion of gun ownership.


—Whether gun ownership correlates with homicide rates in a city.


—How many guns used in homicides were bought legally.


—Where juveniles involved in gun fatalities got their weapons.


—What factors contribute to mass shootings like the Newtown, Conn., one that killed 26 people at a school.


"If an airplane crashed today with 20 children and 6 adults there would be a full-scale investigation of the causes and it would be linked to previous research," said Dr. Stephen Hargarten, director of the Injury Research Center at the Medical College of Wisconsin.


"There's no such system that's comparable to that" for gun violence, he said.


One reason is changes pushed by the National Rifle Association and its allies in 1996, a few years after a major study showed that people who lived in homes with firearms were more likely to be homicide or suicide victims. A rule tacked onto appropriations for the Department of Health and Human Services barred use of funds for "the advocacy or promotion of gun control."


Also, at the gun group's urging, U.S. Rep. Jay Dickey, a Republican from Arkansas, led an effort to remove $2.6 million from the CDC's injury prevention center, which had led most of the research on guns. The money was later restored but earmarked for brain injury research.


"What the NRA did was basically terrorize the research community and terrorize the CDC," said Dr. Mark Rosenberg, who headed the CDC's injury center at the time. "They went after the researchers, they went after institutions, they went after CDC in a very big way, and they went after me," he said. "They didn't want the data to be collected because they were threatened by what the data were showing."


Dickey, who is now retired, said Wednesday that his real concern was the researcher who led that gun ownership study, who Dickey described as being "in his own kingdom or fiefdom" and believing guns are bad.


He and Rosenberg said they have modified their views over time and now both agree that research is needed. They put out a joint statement Wednesday urging research that prevents firearm injuries while also protecting the rights "of legitimate gun owners."


"We ought to research the whole environment, both sides — what the benefits of having guns are and what are the benefits of not having guns," Dickey said. "We should study any part of this problem," including whether armed guards at schools would help, as the National Rifle Association has suggested.


Association officials did not respond to requests for comment. A statement Wednesday said the group "has led efforts to promote safety and responsible gun ownership" and that "attacking firearms" is not the answer. It said nothing about research.


The 1996 law "had a chilling effect. It basically brought the field of firearm-related research to a screeching halt," said Benjamin of the Public Health Association.


Webster said researchers like him had to "partition" themselves so whatever small money they received from the CDC was not used for anything that could be construed as gun policy. One example was a grant he received to evaluate a community-based program to reduce street gun violence in Baltimore, modeled after a successful program in Chicago called CeaseFire. He had to make sure the work included nothing that could be interpreted as gun control research, even though other privately funded research might.


Private funds from foundations have come nowhere near to filling the gap from lack of federal funding, Hargarten said. He and more than 100 other doctors and scientists recently sent Vice President Joe Biden a letter urging more research, saying the lack of it was compounding "the tragedy of gun violence."


Since 1973, the government has awarded 89 grants to study rabies, of which there were 65 cases; 212 grants for cholera, with 400 cases, yet only three grants for firearm injuries that topped 3 million, they wrote. The CDC spends just about $100,000 a year out of its multibillion-dollar budget on firearm-related research, New York Mayor Michael Bloomberg has said.


"It's so out of proportion to the burden, however you measure it," said Dr. Matthew Miller, associate professor of health policy at the Harvard School of Public Health. As a result, "we don't know really simple things," such as whether tighter gun rules in New York will curb gun trafficking "or is some other pipeline going to open up" in another state, he said.


What now?


CDC officials refused to discuss the topic on the record — a possible sign of how gun shy of the issue the agency has been even after the president's order.


Health and Human Services Secretary Kathleen Sebelius said in a statement that her agency is "committed to re-engaging gun violence research."


Others are more cautious. The Union of Concerned Scientists said the White House's view that the law does not ban gun research is helpful, but not enough to clarify the situation for scientists, and that congressional action is needed.


Dickey, the former congressman, agreed.


"Congress is supposed to do that. He's not supposed to do that," Dickey said of Obama's order. "The restrictions were placed there by Congress.


"What I was hoping for ... is 'let's do this together,'" Dickey said.


___


Online:


Violence prevention research: http://www.ucdmc.ucdavis.edu/vprp


CDC injury prevention: http://www.cdc.gov/violenceprevention/nvdrs/


___


Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP


Read More..